INCATE Portfolio

Tackling resistant infections with virulence inhibition.

Invitris developed the worldwide first platform technology to synthesize arbitrary phages within a single system, thus enabling full scalability of therapeutic phage isolation, modification, production, and application.

Myxobiotics is a start-up company discovering and developing novel antibiotics from natural products first isolated and characterized from myxobacteria.

At smartbax we develop novel multi-targeted, antibacterial compounds with extraordinary potency against multi-drug resistant bacteria and difficult-to-treat biofilms.

Developing novel anti-virulence agents for multi drug resistant TB and difficult to treat infectious diseases

An innovative and selective treatment against stomach diseases caused by Helicobacter pylori

Rostra Therapeutics is committed to bringing novel medicines to patients and clinicians delivering the power to restore health and save lives globally

Pedanius Therapeutics is developing RNAi therapeutics using two complimentary, bacterial delivery platform technologies silencing genes critical to bacterial growth and survival, thus introducing a versatile, novel modality into the battle against antimicrobial resistance

AMResolute is an early stage drug discovery and development company combating antibiotic-resistant bacterial infections through innovation, applying customised narrow spectrum antibiotics with a novel mode of action

Olgram is a preclinical stage biotechnology company, creating new drugs to fight bacterial persisters (bacteria in a dormant state responsible for infectious relapses), by using an original approach on new chemical entities discovered in the sea

Fagoterapia LAB is the biotech producing and commercializing tailor-made drugs based on good viruses (phage) to cure antibiotic resistant infections. To develop its products FL will leverage on a technology platform based on a proprietary AI-algorithm and on a phage biobank

OSPT is developing a new material integrating bacteriophage viruses, to produce medical implants reducing surgical site infections and the need for antibiotics

Developing novel Darobactin analogues

The Helmholtz Centre for infection Research together with the Lead Discovery Center develop small molecule-based inhibitors of alpha-hemolysin to treat lung infections caused by Staphylococcus aureus

MyxoBiomedical develops a resistance-breaking macrolide antibiotic based on the myxobacterial natural product scaffold chlorotonil for the treatment of infections caused by MRSA/VRE

Kinzbio is discovering phages that have been overlooked by standard discovery pipelines and have unique and previously unknown biological properties, leveraging their use for infection prevention

At CC Bio, we harness the power of synthetic biology to engineer and edit the microbiome with precision antimicrobials. Our goal is to eliminate microbiome-based disease in a potent, specific and prophylactic fashion, harmonising the relationship between eukaryotic and microbial cells

An antibacterial peptide that inhibits replication and mutagenesis

Life saving therapy for Sepsis based on a protein inspired by nature

Xiretsa is developing a novel class of membrane-modifying antibiotics using a versatile Antimicrobial Conjugated Oligoelectrolytes platform targeting gram-positive and gram-negative pathogens

Interface Biosciences is developing a commensal-derived multifunctional RiPP for the treatment of bacterially-mediated inflammatory disease

With a new mechanism of action, a new class of compound and a new target, Disperazol is a robust, narrow-spectrum drug candidate with significant efficacy in inhibiting and dismantling Pseudomonas aeruginosa biofilms

VIKYNG – AI is a lead generation platform to improve innovations in AMR by combining Artificial Intelligence and a new class of antimicrobials called polypeptoids

Unison Medicines develops small molecule inhibitors of RecA to be used in combination with other front-line antibiotic agents.

LimmaTech Biologics AG is a clinical stage biopharmaceutical company focused on the development and manufacture of next generation vaccines for the prevention of life-threatening diseases.

an ultra-fast, low cost, high-throughput Antimicrobial Susceptibility Test suitable for all bacterial infections